Name : Miss Natnicha Saengsawit Office address : Laboratory of Pharmacology, 4th Floor, Biomedical Science Building, 54 Kamphaeng Phet 6 Talat Bang Khan, Lak si, Bangkok 10210, Thailand Tel : +66 2553 8555 (ext. 3155, 3160) E-mail : [email protected] Research Interests Education 2005-2012 Nawamintrachinutid Suankularbwittayalai Pathumthani Mathematics-Science Program 2012-2016 King Mongkut’s Institute of Technology Ladkrabang Bachelor of Science Program in Industrial Chemistry

Name: Miss Noppawan Rittapai Office address: Laboratory of Pharmacology, 4th Floor, Biomedical Science Building, 54 Kamphaengphet 6 Talat Bang Khen, Laksi, Bangkok 10210, Thailand Tel: +66 2553 8555 (ext. 3155) Email: [email protected] Research Interests: Molecular biology and cell signaling pathway Education: M.Sc. in Applied biological sciences, Chulabhorn Graduate Institute B.Sc. in Medical Technology, Mahidol University

Name: Miss Nedsai Uddin Babar Office address: Laboratory of Pharmacology, 4thFloor, Biomedical Science Building 54 Kamphaeng Phet 6 Talat Bang Khen, Lak Si, Bangkok 10210, Thailand Tel: +66 2553 8555 (ext. 3155) E-mail: [email protected] Research Interests molecular biology, cell signaling and immunotoxicity Education Master ofScience (Applied Biological Science); Chulabhorn Research Institute, Bangkok, Thailand Bachelor of Science (Genetics); Chulalongkorn University, Bangkok, Thailand

Name: Dr. Wanida Cholpraipimolrat Office address: Laboratory of pharmacology, 4 th Floor, Biomedical Science Building, 54 Kamphaeng Phet 6 Talat Bang Khen, Lak Si, Bangkok 10210, Thailand Tel: +66 2553 8555 (ext. 3151) E-mail: [email protected] Research Interests: Molecular mechanism of environmental pollutant with emphasis on metals Metabolic Associated Fatty Liver Disease (MAFLD) Animal models for metabolic diseases Education and Degrees: 2010-2017 Chulabhorn Graduate Institute (International Program) Doctor of Philosophy (Ph.D.) in Environmental toxicology 2003-2008 Kasetsart University Doctor of veterinary medicine (D.V.M) – First Class Honours Professional Memberships: 2009-present Member of Veterinary Council of Thailand Publications: Wisessaowapak C, Worasuttayangkurn L, Maliphol K, Nakareangrit W, Cholpraipimolrat W, Nookabkaew S, Watcharasit P, Satayavivad J.2022. The 28-day repeated arsenic exposure increases tau phosphorylation in the rat brain. Environ Toxicol Pharmacol.95.103970 https://doi.org/10.1016/j.etap.2022.103974 Cholpraipimolrat, W., Suriyo, T., Rangkadilok, N., Nookabkaew, S., Satayavivad, J. 2017. Hijiki and sodium arsenite stimulate growth of human colorectal adenocarcinoma cells through ERK1/2 activation. Food Chem Toxicol, 110, 33–41. https://doi.org/10.1016/j.fct.2017.09.052

Name : Dr. Suthipong Chujan Office address: Laboratory of Pharmacology, 4th Floor, Biomedical Science Building, 54 Kampaeng Phet 6 Talat Bang Khen, Lak Si, Bangkok 10210, Thailand Tel: +66 2553 8555 (ext. 3153) E-mail: [email protected], [email protected] Research Interests Bioinformatics analysis and data mining Genome and transcriptome Network pharmacology and system toxicology Education 2013 B.S. (Medical Sciences), Faculty of Medical science, Naresuan University 2013 LL.B. (Law), Faculty of Law, Naresuan University 2019 Ph.D. (Applied Biological Sciences; International Program) Pharmacology Department, Chulabhorn Graduate Institute (CGI), Chulabhorn Royal Academy Scholarships – His Majesty The King Honor Celebration Scholarships Project for the Scientists Development Award 2011: The 1st prize in oral presentation from Medical Science Academic Annual Meeting MSAM, Faculty of Medical science, Naresuan Unversity. 2017: The 2nd prize in poster presentation from Chulabhorn Royal Academy International Conference; Innovation in Cancer Research and Care, Chulabhorn Royal Academy. Publications Chujan, S., Kitkumthorn, N., Siriangkul, S., & Mutirangura, A. (2014). CCNA1 promoter methylation: a potential marker for grading Papanicolaou smear cervical squamous intraepithelial lesions. Asian Pacific journal of cancer prevention : APJCP, 15(18), 7971–7975. https://doi.org/10.7314/apjcp.2014.15.18.7971 Chujan, S., Suriyo, T., Ungtrakul, T., Pomyen, Y., & Satayavivad, J. (2018). Potential candidate treatment agents for targeting of cholangiocarcinoma identified by gene expression profile analysis. Biomedical reports, 9(1), 42–52. https://doi.org/10.3892/br.2018.1101 Chujan, S., Suriyo, T., & Satayavivad, J. (2019). Integrative In...

Name: Dr. Phanit Songvut Office address: Laboratory of Pharmacology, 4th Floor, Biomedical Science Building, 54 Kamphaeng Phet 6, Talat Bang Khen, Lak Si, Bangkok 10210, Thailand Tel: +66 2553 8555 (ext. 3168) E-mail: [email protected] Research Interests Preclinical and clinical pharmacokinetics Metabolomics Education Doctor of Philosophy, Ph.D. (Pharmacology and Toxicology), Faculty of Pharmacy, Chulalongkorn University Bachelor of Pharmacy (B. Pharm.), Faculty of Pharmacy, Chiangmai University Scholarships Research Attachment Program Student (Metabolomics): Institute of System Biology (INBIOSIS), National University of Malaysia, Malaysia Overseas Research Experience Scholarship (Daniel K. Inouye of Pharmacy, University of Hawaii Hilo, USA) Doctoral Scholarship: The 100th Anniversary Chulalongkorn University for Doctoral Scholarship, Chulalongkorn University, Thailand Graduate Student Scholarship: The Celebration on the Auspicious Occasion of Her Royal Highness Princess Maha Chakri Sirindhorn’s Cycle (60th) Birthday, Thailand Doctoral Scholarship: The 90th Anniversary Chulalongkorn University Fund (Ratchadaphiseksomphot Endowment Fund) IRPUS: Industrial and Research Projects for Undergraduate Students, The Thailand Research Fund (TRF) Awards Graduate Research Excellence in Herbal Medicine 2023, Vichiara Jirawongsae Award, Certificate of Excellence in Herbal Medicine, oral presentation and poster presentation, the 38th International Annual Meeting in Pharmaceutical Sciences “Pharmacokinetics and metabolomics investigation of an orally modified formula of standardized Centella asiatica extract in healthy volunteers” Songvut P, Chariyavilaskul P, Khemawoot P, Tansawat R   The excellent poster presentation award (Herbal and complementary medicine innovation) at the...

Name: Mister Supachai Ritruechai Office address: Laboratory of Pharmacology, 4thFloor, Biomedical Science Building 54 Kamphaeng Phet 6 Talat Bang Khen, Lak Si, Bangkok 10210, Thailand Tel: +66 2553 8555 (ext. 3160) E-mail: Position: Research Assistant Research Interests • Purification of phytochemical compounds from medicinal Plant Education • B.Sc. in Chemistry, Ramkhamhaeng University Area of expertise • Natural products and phytochemistry analysis by HPLC, LC-MS techniques and Spray dry Publications • Changes in the contents of four active diterpenoids at different growth stages inAndrographis paniculata(Burm.f.) Nees (Chuanxinlian). Pholphana N, Rangkadilok N, Saehun J,Ritruechai S, Satayavivad J. Chinese Medicine. 2013; 8:1-12.

Name: Miss Jittra Saehun Office address: Laboratory of Pharmacology, 4thFloor, Biomedical Science Building 54 Kamphaeng Phet 6 Talat Bang Khen, Lak Si, Bangkok 10210, Thailand Tel: +66 2553 8555 (ext. 3163) E-mail: Position: Research Assistant Research Interests • Chemical and heavy metal analysis from medicinal plants, foods and environmental samples Education • Maejo University, B.Sc. in Fisheries Area of expertise • HPLC and ICP-MS technique, analytical chemistry and microwave digestion • Animal handling Publications Evaluation of trace elements in selected foods and dietary intake by young children in Thailand. Nookabkaew S, Rangkadilok N, Akib CA, Tuntiwigit N,Saehun J, Satayavivad J. Food Addit Contam B. 2013; 6:55-67. Changes in the contents of four active diterpenoids at different growth stages inAndrographis paniculata(Burm.f.) Nees (Chuanxinlian). Pholphana N, Rangkadilok N,Saehun J, Ritruechai S, Satayavivad J. Chinese Medicine. 2013; 8:1-12.

Name: Miss Kanjana Chaiyot Office address: Laboratory of Pharmacology, 4thFloor, Biomedical Science Building 54 Kamphaeng Phet 6 Talat Bang Khen, Lak Si, Bangkok 10210, Thailand Tel: +66 2553 8555 (ext. 3158) E-mail: Position: Research Assistant Research Interests • Molecular and cell signalings Education • B.Sc. Biology, Ramkhamhaeng University Area of expertise • Cell culture, Cytotoxicity testing, Immunoblot analysis Presentations Thiantanawat A,Visitnonthachai D,Chaiyot K, Akanimanee J, Auewarakul C, Satayavivad J. Alterations pf p53, cyclin D1, and apoptotic regulators Bcl-2 and Bax in colorectal cancer tissues. The 7th Princess Chulabhorn International Science Congress (PC VII) “Cancer: From basic research to cure”. November 29-December 3, 2012. Shangri-La Hotel, Bangkok, Thailand. (Poster) Suriyo T,Chaiyot K, Watcharasit P, Thiantanawat A, Satayavivad J. Presence and function role of cholinergic system in cancer. The 7th Princess Chulabhorn International Science Congress (PC VII) “Cancer: From basic research to cure”. November 29-December 3, 2012, Shangri-La Hotel, Bangkok, Thailand. (Poster) Suriyo T,Chaiyot K, Watcharasit P, Thiantanawat A, Satayavivad J. Arsenic alters cholinergic system and dysregulates intracellular calcium in microvascular endothelial HMEC-1 cells. The 8th Congress of Toxicology in Developing Countries (8CTDC), Thai Society of Toxicology under the auspices of the IUTOX “Sharing Toxicological Knowledge for Healthy Life & Environment”, September 10-13, 2012, Bangkok, Thailand. Poster I-14, p. 87. Thiantanawat A, Pianjing P, Visitnonthachai D,Chaiyot K, Watcharasit P, Satayavivad J. Estrogenic...

Name: Miss Jaratluck Akanimanee Office address: Laboratory of Pharmacology, 4thFloor, Biomedical Science Building 54 Kamphaeng Phet 6 Talat Bang Khen, Lak Si, Bangkok 10210, Thailand Tel: +66 2553 8555 (ext. 3162) E-mail: Position: Research Scientist Research Interests Pharmaceutical and nutraceutical formulations Education M.Sc. in Pharm. Chulalongkorn University Area of expertise • Screening for antimalarial activity • Pharmaceutical and Nutraceutical formulations Publications Sodium arsenite exposure impairs B cell proliferation and enhances vascular inflammation in Plasmodium berghei mouse model Suntararuks S, Worasuttayangkurn L,Akanimanee J, Suriyo T, Nookabkaew S, ,Srisamut N, Visitnonthachai D, Watcharasit P, Satayavivad J. Environ Toxicol Pharm. 2019; 66: 7-13. In vitroantifungal activities of longan (Dimocarpus longanLour.) seed extract. Rangkadilok N, Tongchusak S, Boonhok R, Chaiyaroj SC, Junyaprasert VB, Buajeeb W,Akanimanee J, Raksasuk T, Suddhasthira T, Satayavivad J. Fitoterapia. 2012; 83:545-53. Conference papers: Akanimanee J, Thiantanawat A, Khamkong P, Rangkadilok, Ritruechai S, Satayavivad J. Effects of Thai’s brown, red, and black rice extracts on in vitro growth of human cancer cell lines. The 7th Princess Chulabhorn International Science Congress (PC VII) “Cancer: From basic research to cure”. November 29-December 3, 2012. Shangri-La Hotel, Bangkok,Thailand. (Poster) Thiantanawat A, Visitnonthachai D, Chaiyot K,Akanimanee J, Auewarakul C, Satayavivad J. Alterations of P53, Cyclin D1and apoptotic regulators BCL2 and BAX in colorectal cancer tissues. The 7th Princess Chulabhorn International Science Congress, Cancer: From basic...

Name: Dr. Jantamas Tuntawiroon Kanitwithayanun Office address: Laboratory of Pharmacology, 4thFloor, Biomedical Science Building 54 Kamphaeng Phet 6 Talat Bang Khen, Lak Si, Bangkok 10210, Thailand Tel: +66 2553 8555 (ext. 3167) E-mail: Position: Research Scientist Research Interests • Impact of environmental pollutants and industrial chemicals, particularly carcinogenic compounds on human health through the use of various biological markers • Oxidative stress and inflammation Education • Doctor of Philosophy (Environmental Toxicology, Technology and Management) Inter-university program between Asian Institute of Technology (AIT), Chulabhorn Research Institute (CRI) and Mahidol University (MU), Thailand Area of expertise • Environmental toxicology study, assessment of the possible harmful effects of carcinogenic pollutants on human health Publications • Glyphosate induces growth of estrogen receptor alpha positive cholangiocarcinoma cells via non-genomic estrogen receptor/ERK1/2 signaling pathway Sritana N, Suriyo T,Kanitwithayanun J, Songvasin BH, Thiantanawat A, Satayavivad J. Food Chem Toxicol. 2018; 118: 595-607. • An engineered cell line lacking OGG1 and MUTYH glycosylases implicates the accumulation of genomic 8-oxoguanine as the basis for paraquat mutagenicity. Tajai P, Fedeles BI, Suriyo T, Navasumrit P,Kanitwithayanun J, Essigmann JM, Satayavivad J. Free Radic Biol Med. 2018;116: 64-72. • Oxidative DNA damage and inflammatory responses in cultured human cells and in humans exposed to traffic-related particles. Vattanasit U, Navasumrit P, Khadka MB,Kanitwithayanun J, Promvijit J, Autrup H, Ruchirawat M. Int J Hyg...

Name: Dr. Benjaporn Homkajorn Songvasin Office address: Research Laboratory of Pharmacology, Chulabhorn Research Institute, 54 Kamphaeng Phet 6 Talat Bang Khen, Lak Si, Bangkok 10210, Thailand Tel: +662-5538555 (ext. 3166) Position: Research scientist, Research Laboratory of Pharmacology, Chulabhorn Research Insitute E-mail: [email protected] Research Interests My research focus is on neurobiology study of affecting brain cells both in vitro and in vivo upon the progression of neurodegenerative diseases. I also experienced in development of novel non-viral/antibody based technology for drug and gene delivery into the brain. At Chulabhorn Research Institute, my main research aim is to investigate neuroprotective effects of Thai medicinal plants on acute and chronic brain disorders. Long-term damage of brain cells would possibly lead to the development of neurodegenerative diseases such as stroke, Alzheimer’s and Parkinson’s diseases. An expected outcome to pursue this aim is for the further development of alternative therapy of active compounds deriving from readily available Thai plants. Education and Degrees Doctor of Philosophy; Flinders University, Adelaide, South Australia (July 2008 – December 2011) Master of Biotechnology Studies, upgraded to Ph.D program; Flinders University, Adelaide, South Australia (July 2006 – July 2008) Bachelor of Science (Biotechnology); Mahidol University, Bangkok, Thailand (June 2002 – July 2006) Academic Activities Research scientist Academic Activities Chulabhom Graduate Institue Environmental Toxicology Course: Integrated Life Sciences (0301501): The central nervous system...