Name: Dr. Benjarath Pupacdi Javed Position: Research Scientist (primarily working with the TIGER-LC project) Office address: Translational Research Unit Chulabhorn Research Institute 54 Kamphaeng Phet 6 Talat Bang Khen, Lak Si, Bangkok 10210, Thailand Research Interests: Data science Bioinformatics Liver Cancer Epidemiology Education and Degrees: Ph.D., Computer Science, Rensselaer Polytechnic Institute, NY, USA, 2007 M.S., Computer Science, Rensselaer Polytechnic Institute, NY, USA, 2002 B.S., Computer Science, The Johns Hopkins University, MD, USA, 2000 High school, The Peddie School, Hightstown, NJ, USA, 1996 ORCID: https://orcid.org/0009-0000-0286-3043 Publications: See my Google Scholar page here.

Name: Dr. Watanyoo Nakareangrit Office Address:Laboratory of pharmacology, 4 th Floor, Biomedical Science Building, 54 Kamphaeng Phet 6, Talat Bang Khen, Lak Si, Bangkok 10210 Thailand Tel: +66 2553 8555 (ext. 3151) E-mail: [email protected] Position:Research Scientist, Translational Research Unit,Chulabhorn Research Institute, Bangkok, Thailand Research Interests Pharmacology and molecular mechanism Environmental toxicology Toxicity testing Laboratory animal research Education and Degrees 2014: Doctor of Philosophy in Environmental Toxicology Chulabhorn Graduate Institute, Thailand 2008: Master of Science in Environmental Engineering and Management Asian Institute of Technology, Thailand 2004: Bachelor of Science in Pharmacy Chulalongkorn University, Thailand Professional Societies Member of The Pharmacy Council of Thailand (2005-present) Publications Visitnonthachai, D., Nakareangrit, W., Suntararuks, S., Chaiyot, K., Watcharasit, P., & Satayavivad, J. (2023). Potentiation of TRAIL-Induced Apoptosis in TRAIL-Resistant Cholangiocarcinoma Cells by Curcumin through the Induction of DR5 Membrane Localization and Disruption of the Anti-Apoptotic Complex DR5/DDX3/GSK3β. Asian Pacific journal of cancer prevention: APJCP, 24(2), 425–434. Wisessaowapak, C., Worasuttayangkurn, L., Maliphol, K., Nakareangrit, W. Cholpraipimolrat, W., Nookabkaew, S., Watcharasit, P., & Satayavivad, J. (2022). The 28-day repeated arsenic exposure increases tau phosphorylation in the rat brain. Environmental toxicology and pharmacology, 95, 103974. Worasuttayangkurn, L., Nakareangrit, W., Kwangjai, J., Sritangos, P., Pholphana, N., Watcharasit, P., Rangkadilok, N., Thiantanawat, A., & Satayavivad, J. (2019). Acute oral toxicity evaluation of Andrographis paniculata-standardized first true leaf...

Name: Mister Akarin Intaramat Office address: Research Laboratory of translational research unit, Chulabhorn Research Institute, 54 Kamphaeng Phet 6 Talat Bang Khen, Lak Si, Bangkok 10210, Thailand Tel: +662-5538555 ext. 3211, +66817500161 (mobile) Position: Researcher, Research Laboratory of translational research unit, Chulabhorn Research Institute E-mail: [email protected] Research Interests Development of immunochromatographic test (ICT) for Diseases: infectious and non-infectious (in human, animals or plants) Bio-markers: hormone, enzyme and tumor marker Food contaminants: toxins or microorganisms Environmental pollution: pesticide, chemical agents or microorganisms Study on the improvement of ICT performance: sensitivity and specificity Education and Degrees B.Sc., Medical technology, Thammasat University, Thailand, 2001 M.Sc., Microbiology, Mahidol University, Thailand, 2006 Publications A. Research Articles in International Journals 1. Chareonsirisuthigul T, Khositnithikul R, Intaramat A, Inkomlue R, Sriwanichrak K, Piromsontikorn S, et al. Performance comparison of immunodiffusion, enzyme-linked immunosorbent assay, immunochromatography and hemagglutination for serodiagnosis of human pythiosis. Diagnostic microbiology and infectious disease. 2013;76(1):42-5. 2. Intaramat A, Sornprachum T, Chantrathonkul B, Chaisuriya P, Lohnoo T, Yingyong W, et al. Protein A/Gbased immunochromatographic test for serodiagnosis of pythiosis in human and animal subjects from Asia and Americas. Med Mycol. 2016;54(6):641-7. 3. Krajaejun T, Imkhieo S, Intaramat A, Ratanabanangkoon K. Development of an immunochromatographic test for rapid serodiagnosis of human pythiosis. Clinical and vaccine immunology : CVI. 2009;16(4):506-9. 4. Pruksaphon K, Intaramat A, Ratanabanangkoon K, Nosanchuk...

Name: Miss Anong Piwkam Office address: Translational research unit, Chulabhorn Research Institute, 54 Kamphaeng Phet 6 Talat Bang Khen, Lak Si, Bangkok 10210, Thailand Tel: +662-5541900 ext. 2821 (office), +6695-9141528 (mobile) Position: Researcher scientist, Translational research unit, Chulabhorn Research Institute E-mail: [email protected] Research Interests Biotherapeutic protein characterization Protein characterization by using capillary electrophoresis Bacterial endotoxin determination Education and Degrees B.Sc. in Biotechnology (First Class Hons.), School of Science, Mae Fah Luang University, Chiang Rai, Thailand (2008) M.Sc. in Applied Biological Sciences, Chulabhorn Graduate Institute, Bangkok, Thailand (2010) Publications Buranajitpakorn S, Piwkam A, Vattanaviboon P, and Mongkolsuk S. Genes for hydrogen peroxide detoxification and adaptation contribute to protection against heat stress of Xanthomonas campestris pv. campestris. FEMS Microbiol Lett. 2011;317(1):60-6. Charoenlap N, Sornchuer P, Piwkam A, Srijaruskul K, Mongkolsuk S, Vattanaviboon P. The roles of peroxide protective regulons in protecting Xanthomonas campestris pv. campestris from sodium hypochlorite stress. Can J Microbiol. 2015;61(5):343-50. Presentations Tit-oon P, Khongmanee A, Tianpanich K, Piwkam A, Wajeesaksit S, Ruchirawat M, Fuangthong M. Enhanced antibody production by lowering culture temperature of suspension HEK293 cells. 17th International Symposium of the Protein Society of Thailand, 2022. Anong Piwkam, Thanong Phueaouan, Jutamart Monkai, Uraporn Sardsud and Ekachai Chukeatirote. Screening and isolation of rhizobacteria exhibiting antagonistic activity against Lasiodiplodia thebromae. The 34th Congress on Science and Technology of Thailand, “Science and...

Name: Miss Nuengthida Suesattarat Office address: Translational research unit, Chulabhorn Research Institute, 54 Kamphaeng Phet 6 Talat Bang Khen, Lak Si, Bangkok 10210, Thailand Tel: +662-5541900 ext. 2611 (office), +6689-0420331 (mobile) Positions: Research assistant, Translational research unit, Chulabhorn Research Institute E-mail: [email protected] Research Interests Molecular technique Mammalian cell culture Cell line development for recombinant protein Upstream process development and process scale-up Education and Degrees B.Sc. in Industrial microbiology, King Mongkut’s Institute of Technology Ladkrabang, Bangkok, Thailand (2015)

Name: Sukanya Eursakun Office address:Research Laboratory of Translational Research Unit, Chulabhorn Research Institute, 54 Kamphaeng Phet 6 Talat Bang Khen, Lak Si, Bangkok 10210, Thailand Tel: +662-5538555 ext. 3211 (office), +66 968820899 (mobile) Position: Research scientist, Research Laboratory of Translational Research Unit, Chulabhorn Research Institute E-mail: [email protected] Research Interests Molecular techniques Immunological techniques Protein Purification and characterization Cell culture Cell-based potency assay Biosimilar bio-assay Education and Degrees B.Sc. (1st Hons) Biochemistry, Faculty of science, Kasetsart University, 2006 M.Sc. Chemical Biology, Chulabhorn Graduate Institute, 2011 Publications Ratanabanangkoon K*, Tan K, Eursakun S, Tan C, Simsiriwong P, Pamornsakda T, Wiriyarat W, Klinpayorn C, Tan N. A Simple and Novel Strategy for the Production of a Pan-specific Antiserum against Elapid Snakes of Asia. PLos Negl Trop Dis. 2016;(4):e0004565. Ratanabanangkoon K*, Simsiriwong P, Pruksaphon K, Tan K, Eursakun S, Tan C, Chantrathonkul B, Wongwadhunyoo W, Youngchim S, Tan N. A novel in vitro potency assay of antisera against Thai Naja kaouthia based on nicotinic acetylcholine receptor binding. Sci Rep. 2017;7(1):8575. Ratanabanangkoon K*, Simsiriwong P, Pruksaphon K, Tan K, Chantrathonkul B, Eursakun S, Tan C. An in vitro potency assay using nicotinic acetylcholine receptor binding works well with antivenoms against Bungarus candidus and Naja naja. Sci Rep. 2018;8:9716. อนุสิทธิบัตร : 18745 เรื่อง กรรมวิธีในการผลิตเซรุ่มแก้พิษงูหลายชนิดแบบแพนสเปซิฟิก (Pan-specific antivenom) (ได้รับแล้ว) สิทธิบัตร คำขอเลขที่ 1701003769 กรรมวิธีการวัดประสิทธิภาพการแก้พิษงูของเซรุ่มแก้พิษงูประเภทพิษต่อระบบประสาทในหลอดทดลอง (ระหว่างยื่นขอ)

Name: Miss Sarocha Dungkeaw Office address: Research Laboratory of Translational Research Unit, Chulabhorn Research Institute, 54 Kamphaeng Phet 6 Talat Bang Khen, Lak Si, Bangkok 10210, Thailand Tel: +662-5541900 ext. 2821, 2611 (office), +6692-9089809 (mobile) Position: Assistant researcher, Research Laboratory of Translational Research Unit, Chulabhorn Research Institute E-mail: [email protected] Research Interests Cell line and process development: Performed cell line development for leads candidate of biosimilars as well as new biologics especially for monoclonal antibody. Process scale-up: Set-up and optimization for process scale-up from shaker flask to bench scale bioreactor (using single-use and multi-use bioreactor) up to 1000L pilot scale and production scale. Drug quality control: Set up and optimization for biologics characterization titer measurement using Octet, Western-blot etc. Education and Degrees B.A. Department of Food Science, Faculty of Agricultural Product Innovation and Technology (APIT) Srinakharinwirot University, Thailand.

Name: Mister Sivakorn Wajeesaksit Office address: Translational Research Unit, Chulabhorn Research Institute, 54 Kamphaeng Phet 6 Talat Bang Khen, Lak Si, Bangkok 10210, Thailand Tel: +662-5541900 ext. 2611 Position: Research Assistant, Translational Research Unit, Chulabhorn Research Institute E-mail: [email protected] Education and Degrees Chulalongkorn University, 2011-2014 B.Sc. Sciences (Chemistry), Chulalongkorn University, Thailand., 2014

Name: Worasamon Chintana Office address: Translational Research Unit, Chulabhorn Graduate Institute, 54 Kamphaeng Phet 6 Talat Bang Khen, Lak Si, Bangkok 10210, Thailand Tel: +662-5541900 ext. 2620 (office), +669-61525622 (mobile) Position: Research scientist, Translational Research Unit Chulabhorn Research Institute E-mail: [email protected] Education and Degrees B.Sc. Sciences (Microbiology), Chulalongkorn University, Thailand, 2007 M.Sc., Biotechnology, Mahidol University, Thailand, 2015

Name: Mrs. Ratiphorn Sirichaichanakul Office address:Research Laboratory of Translational Research Unit, Chulabhorn Research Institute, 54 Kamphaeng Phet 6 Talat Bang Khen, Lak Si, Bangkok 10210, Thailand Tel: +662-5538555 ext. 3211 (office), +6684-4092145 (mobile) Position: Research Scientist, Research Laboratory of Translational Research Unit, Chulabhorn Research Institute Email:[email protected] Research Interests Molecular Biotechnology Microbiology Biosimilar Immunotherapy Pharmacokinetics Pharmacodynamics Toxicology Non-clinical Study Hybridoma Bioassay Education and Degrees B. Sc. Microbiology, Faculty of Science, Srinakharinwirot University, 2006-2009 M. Sc. Molecular and medical Biotechnology, Faculty of Science, Mahidol University, 2010-2014

Name: Miss Pavinee Simsiriwong Office address: Research Laboratory of Translational Research Unit, Chulabhorn Research Institute, 54 Kamphaeng Phet 6 Talat Bang Khen, Lak Si, Bangkok 10210, Thailand Tel: +662-5538555 ext. 3211 (office), +661-4590220 (mobile) Positions: Research Laboratory of Translational Research Unit, Chulabhorn Research Institute Email: [email protected] Research Interests 1. Molecular biotechnology 2. Biosimilar 3. Immunology 4. Bioassay Education and Degrees: • M.Sc., Applied Biological Sciences: Environmental and Health, Chulabhorn Graduate Institute, Thailand, 2011 • B.Sc., Biochemistry, Kasetsart University, Thailand, 2006

Name: Mister Bhawat Wongkhamprai Office address: Translational research unit, Chulabhorn Research Institute, 54 Kamphaeng Phet 6 Talat Bang Khen, Lak Si, Bangkok 10210, Thailand Tel: +662-5541900 ext. 2821 (office), +6692-8919544 (mobile) Positions: Researcher scientist, Translational research unit, Chulabhorn Research Institute E-mail: [email protected] Research Interests 1. Biotherapeutic protein characterization 2. Mass spectrometry 3. Proteomics 4. Impurities (Mycoplasma, hcDNA) in biopharma production Education and Degrees: – B.Sc. in Biotechnology, Naresuan University, Phitsanulok, Thailand (2008) – M.Sc. (Genetic Engineering), Kasetsart University, Bangkok, Thailand (2011) Work Experience: – Research Scientist (2012 – 2014) Laboratory of Biotechnology, Chulabhorn Research Institute. – Research Scientist (2015 – present) Translational research unit, Chulabhorn Research Institute. Publications: – Wongkhamprai, B., Sangsavang, K., Sriboonlert, A., Huehne, P. S. (2011). Efficiency of Agrobacterium transformation of pinene synthase gene isolated from kaffir lime in Arabidopsis thaliana. Thai Journal of Genetics 4(2), 85-93. – Ratanasut K., Wongkhamprai B., and Maknoi S. (2011). Expression of a novel cytochrome P450, CYP76AB1 correlates with the sequential whiteblue-white colour transition of Vanda coerulea petals. Biologia Plantarum 55(2): 353-356 – Patipipat P, Bhinija K, Wongkhamprai B, Huehne P*. Molecular cloning of arsenate reductase and phytochelatin synthase genes related to arsenic response in Oryza sativa L. ssp. Indica cv. Khao Dawk Mali 105. Thai J Genet. 2014;7(1):41-50. Presentations: – Huehne P, Satayavivad J, Wongkhamprai B, Bhinija K. (2015) Identification...