Adaptive protection and cross-resistance to antibiotics of Stenotrophomonas maltophilia mediated by biocides: Molecular mechanisms

Aroonkit, P.; Thongsornkleeb, C.; Tummatorn, J.; Krajangsri, S.; Mungthin, M.; Ruchirawat, S. Synthesis of Isocryptolepine Analogues and Their Structure–Activity Relationship Studies as Antiplasmodial and Antiproliferative Agents. Eur. J. Med. Chem. 2015, 94, 56–62.

A structure-based virtual high-throughput screening, molecular docking, molecular dynamics and MM/PBSA study identified novel putative drug-like dual inhibitors of trypanosomal cruzain and rhodesain cysteine proteases Eurtivong C, Zimmer C, Schirmeister T, Butkinaree C, Saruengkhanphasit R, Niwetmarin W, Ruchirawat S, Bhambra AS Mol Divers. 2023. (In press)