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Medicinal Chemistry

Medicinal Chemistry

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Substituted 1,4-naphthoquinones for potential anticancer therapeutics: In vitro cytotoxic effects and QSAR-guided design of new analogs

Prachayasittikul V*, Mandi P, Pingaew R*, Prachayasittikul S, Ruchirawat S

Comput Struct Biotechnol J. 2025;27:3492-509.

Synthesis and evaluation of Tacrinocerins, Tacrine Hybrids with α-Onocerin from Phlegmariurus nummulariifolius (Blume) Ching, as a novel class of acetylcholinesterase inhibitor

Ngernnak C, Wongsuwan S, Ruchirawat S, Thasana N*

Chem Asian J. 2025.

Palladium-catalyzed hydroarylation of N-propargyl benzamides: A direct route to N-allylbenzamides and acid-induced cyclization to oxazolines

Tanomsiri G, Tummatorn J*, Thongsornkleeb C, Ruchirawat S

J Org Chem. 2025. (Inpress Article)

Bi(OTf)3-catalyzed cascade cycloaddition-decarbonylation-n-deoxygenative aromatization between
2-arylisatogens and styrenes: Unveiling a synthesis of 2,4-diarylquinolines

Punjajom K, Chonradeenitchakul S, Tummatorn J, Ruchirawat S, Thongsornkleeb C

Org Lett. 2024. (Inpress Article)

Cyclopropyl carbinol: A versatile motif for the synthesis of diene and naphthalene compounds under ultra-low loading of catalytic bismuth(III) trifluoromethanesulfonate

Saewa R, Tummatorn J, Thongsornkleeb C, Ruchirawat S

Asian J Org Chem. 2025;14(6):e202500208.

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