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Medicinal Chemistry

Medicinal Chemistry

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Cascade Cyclization of o‑(2-Acyl-1-ethynyl)benzaldehydes with Amino Acid Derivatives: Synthesis of Indeno[2,1‑c]pyran-3-ones and 1 Oxazolonylisobenzofurans via the Erlenmeyer−Plöchl Azlactone Reaction.

Worayuthakarn R, Suddee N, Theppitak C, Chainok K, Ruchirawat S, Thasana N*.

ACS Omega. 2024;-.

Unveiling Route for the Synthesis of Tröger’s Bases Through Azide Rearrangement.

Jaithum K, Tummatorn J*, Thongsornkleeb C, Ruchirawat S.

Chem Asian J. 2024;-.

Huperzine A Regulates the Physiological Homeostasis of Amyloid Precursor Protein Proteolysis and Tau Protein Conformation—A Computational and Experimental Investigation.

Wongjaikam S, Nopparat C, Boontem P, Panmanee J, Thasana N, Shukla M, Govitrapong P*.

Biology. 2024;13:518.

Cholinesterase Inhibitory Activity and Molecular Docking Studies of Isocryptolepine-Triazole Adducts.

Tummatorn J*, Meewan I, Khunnawutmanotham N, Chimnoi N, Suwanwong N, Rodphon W, Thongsornkleeb C, Yang J, Ruchirawat S.

ChemMedChem. 2024;-.

Cytotoxic stress caused by azalamellarin D (AzaD) interferes with cellular protein translation by targeting the nutrient-sensing kinase mTOR.

Meerod T, Sangsuwan R, Klumthong K, Chantrathonkul B, Phutubtim N, Govitrapong P, Ruchirawat S, Ploypradith P, Sopha P*.

J Biochem. 2024;-.

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