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Medicinal Chemistry

Medicinal Chemistry

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Identification of antiproliferative nogalamycin series as potent inhibitors of EGFR tyrosine kinase: an in vitro and computational study

Eurtivong C, Lamtha T, Jiwacharoenchai N, Yang MC, Saruengkhanphasit R, Niwetmarin W, Maiuthed A, Tabtimmai L, Seetaha S, Ruchirawat S, Choowongkomon K

Chem-Biol Interact. 2026;436:112217.

One-pot sequential aerobic oxidation/1,3-dipolar cycloaddition/α-iminol rearrangement of 1-benzyl-3,4-dihydroisoquinolines with iso(thio/seleno)cyanates: a facile synthesis of tetrahydroisoquinoline-fused-(thio/seleno)hydantoin derivatives.

Limjirawatthana S, Ploypradith P, Ruchirawat S, Theppitak C, Ieawsuwan W

ACS Org Inorg Au. 2026. doi.10.1021/acsorginorgau.6c00023.

Reductant-free NiF2/picolinic acid-catalyzed coupling-cyclization of 2-iodobenzamides with malonates.

Tanomsiri G, Takaoka J, Tummatorn J*, Thongsornkleeb C, Ruchirawat S

J Org Chem. 2026;91(26):8868-8880.

Visible light-driven Pd-catalyzed carbonylative C(sp3)–H functionalization at room temperature and 1 bar of CO gas

Chuentragool P*, Thitseesaeng W, Ngamnithiporn A, Ruchirawat S

Asian J Org Chem. 2026;15(6):e70461.

Molecular mechanisms and network pharmacology revealing therapeutic potential of acetamidosulfonamides against parkinsonian model

Ruankham W, Prachayasittikul V, Pingaew R, Tantimongcolwat T, Worachartcheewan A, Chompon K, Ruchirawat S, Prachayasittikul V, Prachayasittikul S, Phopin K

ACS Omega. 2026;11(21):31459-31476.

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