CRI Office Hour : Monday - Friday, 09.00 - 17.00

+66 2553 8555

+66 2553 8527

Display
Center for Biologics Research and Development

Center for Biologics Research and Development

CRI’s Center for Biologics Research and Development (CBRD) was founded with the intention to bridge the gap between drug development at laboratory scale and the clinical use, i.e., from bench to bedside. The development of biologics starts from the generation of cell line that produced biologics of interest, product. characterization, proof of the efficacy in vitro and in vivo, toxicity testing, and clinical studies. The process development and scale up to the production of biologics for clinical use with GMP-compliance is also an important step in the drug development.

The ultimate goal of CBRD is to improve the quality of life of Thai people by enabling accessibility and affordability to high quality biotherapeutics. The disease scope includes cancers, infectious diseases, and rare diseases. The first success case is the development of trastuzumab biosimilar from basic cell line engineering to pilot scale production and preclinical (animal) study. The production scale and clinical study are in the process. Another goal of CBRD is to be a training center for biopharmaceutical industry for CGI students as well as external researchers who interested to re-skill and up-skill in this arena. Collectively, CBRD contributes a supportive role in building research knowledge, develop human resource as well as provide infrastructure capability in an emergency situation to drive Thailand economic growth and pertain biosecurity for a good health and well-being society of Thai people.

See All

Research & Academic Activities

Biopharmaceutical drug development
Process development and scale-up production

Research

Below are the research focuses of Lab Immunology:

1. Development of simple diagnostic tests for antigens/antibodies relevant to health problems in Thailand and other countries.2. Development of in vitro assays to reduce and/or replace the use of experimental animals.

See All

Activities

Development of a GNA-lectin based immunochromatographic test for rapid diagnosis in human penicilliosis marneffei
Rapid diagnostic test to detect specific microbial nucleotide sequences
Immunochromatographic test for rapid diagnosis of human pythiosis
Development of immunochromatographic tests for simple diagnosis of human gnathostomiasis caused by Gnathostoma spinigerum
Antivenom
Production of a pan-specific antivenom against elapid snakes

Contact

Center for Biologics Research and Development

Chulabhorn Research Institute

54 Kamphaeng Phet 6 Rd., Talat Bang Khen, Lak Si, Bangkok 10210 THAILAND

Telephone

+66 2554 1900
ext.2713

Fax -

Report broken file
File Broken

profile

We use cookies to improve performance. and good experience using your website. You can study details at Cookies policy and can manage your own privacy by clicking on Settings

Privacy Preferences

You can choose your cookie settings by turning them on/off. Cookies of each category are available on request, except essential cookies.

Allow All
Manage Consent Preferences
  • Necessary
    Always Active

    Necessary cookies are absolutely essential for the website to function properly. These cookies ensure basic functionalities and security features of the website, anonymously.

  • Analytics

    Analytical cookies are used to understand how visitors interact with the website. These cookies help provide information on metrics the number of visitors, bounce rate, traffic source, etc.

Save