CRI Office Hour : Monday - Friday, 09.00 - 17.00

+66 2553 8555

+66 2553 8527

Laboratory of Chemical Carcinogenesis

Laboratory of Chemical Carcinogenesis

Director: Professor Dr. Her Royal Highness Princess Chulabhorn Krom Phra Srisavangavadhana

Cancer is a group of diseases characterized by abnormal growth and proliferation. These abnormalities result from a number of biochemical and pathological processes. The etiology of cancer is complex and involves multiple and diverse factors. In 2020, there were more than 190,000 new cancer cases reported in Thailand with liver as the most common cancer site in men. The prevalence of liver cancer in Thailand is sixth highest in the world. The two main types of liver cancers in Thailand are hepatocellular carcinoma (HCC) and cholangiocarcinoma (CCA). While the distribution of HCC incidence is similar throughout the country, CCA distribution shows large variation geographically. Northeastern Thailand has an incidence rate of 85 per 100,000 which is the highest rate worldwide.

The fluctuations of cancer frequency, coupled with observed changes in the temporal trends, suggest that genetic predisposition, environmental and lifestyle factors play an important role in carcinogenesis, a multistep and multicausal process involving changes in the genome or in the expression of specific genes that regulate normal function and growth of the cells.


  • To study the mechanisms underlying cancer development particularly in systems prevalent in Thailand and in South-east Asia which may be induced by chemicals and other agents
  • To study genetic and other molecular alterations in certain types of cancers and their relevance to etiology and pathogenesis
  • To identify and evaluate new target for cancer treatment and potential diagnosis markers
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Research & Academic Activities Page


Laboratory of Chemical Carcinogenesis

Chulabhorn Research Institute

3rd Floor, Biomedical Science Building

54 Kamphaeng Phet 6 Rd., Talat Bang Khen, Lak Si, Bangkok 10210 THAILAND


+66 2553 8555
ext. 8255, 8256

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