Name : Dr. Nisachon Khunnawutmanotham (Research Scientist I) Office Address : Room : R310 / R303C Laboratory of Organic Synthesis 54 Kamphaeng Phet 6 Talat Bang Khen, Lak Si, Bangkok 10210, Thailand Tel : +66 2553 8555 (ext. 3026, 3024) Email : [email protected] Research Interests Organic synthesis Natural products with biological activities Education 1999 – 2003 Ph.D Chemistry, Kasetsart University, Bangkok, Thailand 1996 – 1998 M.Sc. Chemistry, Kasetsart University, Bangkok, Thailand 1992 – 1995 B.Sc. Chemistry, Kasetsart University, Bangkok, Thailand Work Experiences 2004 – present Research Scientist, Chulabhorn Research Institute, Thailand Awards 2004 Royal Golden Jubilee Scholarship 1999 Student Scholarship from Development and Promotion of Science and Technology Talents (DPST) 1999 Dr.Tab Nilanidhi Prize from Dr.Tab Nilanidhi’s foundation Publications Selected Publications Khunnawutmanotham, N.;Chimnoi, N.;Nangkoed, P.;Wiwattanapaisarn, W.;Techasakul, S. Facile Extraction of Three Main Indole Alkaloids from Mitragyna speciosa by Using Hot Water. ChemistrySelect 2021, 6, 10221–10225. Khunnawutmanotham, N.;Laongthipparos, C.;Saparpakorn, P.;Chimnoi, N.;Techasakul, S. Synthesis of 3-Aminocoumarin-N-Benzylpyridinium Conjugates with Nanomolar Inhibitory Activity against Acetylcholinesterase. Beilstein J. Org. Chem.2018, 14, 2545–2552. Khunnawutmanotham, N.;Sahakitpichan, P.;Chimnoi, N.;Techasakul, S. Efficient One-Pot Synthesis of Tetrahydronaphtho[2,1-f]isoquinolines by Using Domino Pictet–Spengler/Friedel–Crafts-Type Reactions. Eur. J. Org. Chem. 2017, 2017, 6434–6440. Khunnawutmanotham, N.;Chimnoi, N.;Saparpakorn, P.;Techasakul, S. Synthesis and Anti-acetylcholinesterase Activity of Scopoletin Derivatives. Bioorg. Chem.2016, 65, 137–145. Khunnawutmanotham, N.;Sahakitpichan, P.;Chimnoi, N.;Techasakul, S. Divergent Total Syntheses to Azafluoranthene and Dehydroaporphine Alkaloids. Eur. J....

Name : Miss Thanyaluck Thanyacharoen (Research Scientist I) Office Address : Room : R311/R303B Laboratory of Biochemistry 54 Kamphaeng Phet 6 Talat Bang Khen, Lak Si, Bangkok 10210, Thailand Tel : +66 2553 8555 (ext. 3016) Email : [email protected] Research Interests Biomedical materials Anti-oxidant activity of composite polymer Education 2016 – 2017 M.Sc. Material Innovation and Technology, Thammasat University, Thailand. 2012 – 2015 B.A. Chemistry, Nakhon Sawan Rajabhat University , Thailand. (First Class Honors) Work Experiences 2020 – present Research Scientist, Chulabhorn Research Institute, Thailand 2018 – 2019 Research Assistant, Chulabhorn Research Institute, Thailand Publications Selected Publications Muangsri, R.; Chuysinuan, P.; Thanyacharoen, T.; Techasakul, S.; Sukhavattanakul, P.; Ummartyotin, S. Release Characteristic and Antioxidant Activity 1 of 4-Hydroxybenzoic Acid (4HB) from Sodium Alginate and Polyvinyl Alcohol-based Hydrogel. ChemistrySelect. 2022, 34, 1. Muangsri, R.; Chuysinuan, P.; Thanyacharoen, T.; Techasakul, S.; Sukhavattanakul, P.; Ummartyotin, S. Utilization of Freeze Thaw Process for Polyvinyl Alcohol/Sodium Alginate (PVA/SA) Hydrogel Composite. JMMM. 2022, 32, 34-41. Chuysinuan, P.; Nooeaid, P.; Thanyacharoen, T.; Techasakul, S.; Pavasant, P.; Kanjanamekanant, K. Injectable Eggshell-Derived Hydroxyapatite-Incorporated Fibroin-Alginate Composite Hydrogel for Bone Tissue Engineering. Int. J. Biol. Macromol. 2021, 193(Part A), 799-808. Kotcharat, P.; Chuysinuan, P.; Thanyacharoen, T.; Techasakul, S.; Ummartyotin, S. Development of Bacterial Cellulose and Polycaprolactone (PCL) Based Composite for Medical Material. Sustain Chem. Pharm. 2021, 20, 100404. Chuysinuan, P.; Chunshom, N.;...

Name : Miss Bunkuea Chantrathonkul (Research Assistant) Office Address : Room : 1704 CGI Laboratory of Medicinal Chemistry 54 Kamphaeng Phet 6 Talat Bang Khen, Lak Si, Bangkok 10210, Thailand Tel : +66 2554 1900 (ext. 2727) Email : [email protected] Research Interests Biological activities Small molecule compounds Drug-like compounds Education 1995-1999 B.A. Apply Biology, Suan Sunandha Institute, Thanland Work Experiences 2004 – present Research Assistant, Chulabhorn Research Institute, Thailand Publications Selected Publications Sopha P, Phutubtim N, Chantrathonkul B, Ploypradith P, Ruchirawat S,Chittchang M. Roles of autophagy in relation to mitochondrial stress responses of HeLa cells to lamellarin cytotoxicity. Toxicology. 2021;462:152963. Other Publications Intaramat A, Sornprachum T, Chantrathonkul B, Chaisuriya P, Jongruja N, Kumsang Y, Sandee A, Santurio J, Grooters A, Ratanabanangkoon K. Protein A/G-based immunochromatographic test for serodiagnosis of pythiosis in human and animal subjects from Asia and Americas. Med Mycol. 2016;54(6):641-7. Ratanabanangkoon K*, Simsiriwong P, Pruksaphon K, Tan K, Eursakun S, Tan C, Chantrathonkul B, Wongwadhunyoo W, Youngchim S, Tan N. A novel in vitro potency assay of antisera against Thai Naja kaouthia based on nicotinic acetylcholine receptor binding. Sci Rep. 2017;7(1):8575. Ratanabanangkoon K*, Simsiriwong P, Pruksaphon K, Tan K, Chantrathonkul B, Eursakun S, Tan C. An in vitro potency assay using nicotinic acetylcholine receptor binding works well with antivenoms against Bungarus candidus and Naja naja. Sci Rep. 2018;8:9716.

Name : Dr. Aurapat Ngamnithiporn (Research Scientist) Office Address : Room : R413 / R403A Laboratory of Medicinal Chemistry 54 Kamphaeng Phet 6 Talat Bang Khen, Lak Si, Bangkok 10210, Thailand Tel : +66 2553 8555 (ext. 3042) Email : [email protected] Research Interests Synthetic methodology Asymmetric catalysis Total synthesis of natural products Education 2018 – 2021 Ph.D Organic Chemistry, California Institute of Technology, U.S.A. 2015 – 2018 M.Sc. Organic Chemistry, California Institute of Technology, U.S.A. 2011 – 2015 B.A. Chemistry, Magna cum laude, Carleton College, U.S.A. Work Experiences 2021 – present Research Scientist, Chulabhorn Research Institute, Thailand Awards 2010 – 2021 Royal Thai Government Scholarship 2015 ACS Undergraduate Award in Organic Chemistry, U.S.A. 2015 Sigma Xi Undergraduate Research Award, Carleton College, U.S.A. 2015 Richard Ramette Teaching Award, Carleton College, U.S.A. 2015 Phi Beta Kappa National Honor Society, Carleton College, U.S.A. 2015 Jerry Mohrig Prize in Chemistry, Carleton College, U.S.A. Publications Selected Publications Ngamnithiporn, A.; Chuentragool, P.; Ploypradith, P.; Ruchirawat, S. Syntheses of 3-Aryl Tetrahydroisoquinolines via an Intermolecular [4 + 2] Cycloaddition of Sultines with Imines. Org. Lett. 2022, 24, 4192–4196. Kim, A. N.; Ngamnithiporn, A.; Bartberger, M. D.; Stoltz, B. M. Iridium-Catalyzed Asymmetric Trans-Selective Hydrogenation of 1,3-Disubstituted Isoquinolines. Chem. Sci. 2022, 13, 3227–3232. Kim, A. N.;* Ngamnithiporn, A.;* Welin, E. R.; Daiger, M. T., Grunanger, C. U.; Bartberger, M. D.;...

Name : Dr. Sakunchai Khumsubdee (Research Scientist) Office Address : Room : R512 / R403A Laboratory of Medicinal Chemistry 54 Kamphaeng Phet 6 Talat Bang Khen, Lak Si, Bangkok 10210, Thailand Tel : +66 2553 8555 (ext. 3048) Email : [email protected] Research Interests Synthetic methodology Organometallic catalysis Biological active metal synthesis Education 2015 – 2017 Postdoc Organic Chemistry, Massachusetts Institute of Technology, U.S.A. 2007 – 2013 Ph.D Organic Chemistry, Texas A&M University, U.S.A. 2002 – 2006 B.A. Chemistry, Mahidol University, THAILAND Work Experiences 2014 – present Research Scientist, Chulabhorn Research Institute, Thailand Awards 2007 – 2013 Royal Thai Government Scholarship 2002 – 2006 Sritrang Thong Scholarship, Mahidol University, THAILAND Publications Selected Publications Thongararm, P.; Fedeles, B. I.; Khumsubdee, S.; Armijo, A. L.; Kim, L.; Thiantanawat, A.; Promvijit, J.; Navasumrit, P.; Ruchirawat, M.; Croy, R. G.; Essigmann, J. M.* Modulation of N-Methyl-N-nitrosourea Mutagenesis in Mouse Embryo Fibroblasts Derived from the gpt Delta Mouse by an Inhibitor of the O6-Methylguanine Methyltransferase, MGMT. Chem. Res. Toxicol. 2020, 33, 625-633. Khumsubdee, S.; Burgess, K.* Metathesis for catalyst design: metacatalysis. Tetrahedron 2014, 70, 1326-1335. Khumsubdee, S.; Zhou, H.; Burgess, K.* Homo-Roche Ester Derivatives by Asymmetric Hydrogenation and Organocatalysis. J. Org. Chem. 2013, 78, 11948-11955. Khumsubdee, S.; Fan, Y.; Burgess, K.* A Comparison between Oxazoline-imidazolinylidene, – imidazolylidine, -benzimidazolylidene Hydrogenation Catalysts. J. Org. Chem. 2013, 78, 9969-9974....

Name : Dr. Winai Ieawsuwan (Research Scientist) Office Address : Room : R514B / R303C Laboratory of Medicinal Chemistry 54 Kamphaeng Phet 6 Talat Bang Khen, Lak Si, Bangkok 10210, Thailand Tel : +66 2553 8555 (ext. 3052, 3024) Email : [email protected] Research Interests Synthetic methodology Asymmetric catalysis Total synthesis of natural products Education 2005 – 2009 Dr. Phil. Nat Organic Chemistry, Goethe University Frankfurt am Main, Germany 2001 – 2004 M.Sc. Organic Chemistry, Mahidol University, Thailand 1997 – 2001 B.Sc. Chemistry, Silpakorn University, Thailand Work Experiences 2020 – present Research Scientist I, Chulabhorn Research Institute, Thailand 2011 – 2020 Research Scientist, Chulabhorn Research Institute, Thailand 2009 – 2010 “Postdoctoral researcher, Université catholique de Louvain, Belgium.” 2008 “Laboratory assistant for organic chemistry course, Goethe University Frankfurt am Main, Germany.” 2004 – 2005 Research assistant, Mahidol University, Bangkok, Thailand. Awards 1997 – 2004 The Development and Promotion of Science and Technology Talent Project (DPST) Scholarship 2002 – 2004 The Postgraduate Education and Research Program in Chemistry (PERCH). 2005 – 2009 Degussa Endowed Professorship from Prof. Dr. Magnus Rueping. 2009 – 2010 Postdoctoral fellowship from Prof. Dr. Istvan E. Marko. 2013 “Good Award on the thesis award 2013” National Research Council of Thailand (NRCT), Thailand 2007 IUPAC Poster Prize at The German Chemical Society Biennial Congress: “GDCh Chemistry Forum” (Wissenschaftsforum Chemie), University...

Name : Dr. Wannaporn Disadee (Research Scientist I) Office Address : Room : R614B/R603 Laboratory of Medicinal Chemistry 54 Kamphaeng Phet 6 Talat Bang Khen, Lak Si, Bangkok 10210, Thailand Tel : +66 2553 8555 (ext. 3081, 3090, 3091) Email : [email protected] Research Interests One-pot Tandem Reaction and Green Synthetic Methodology Organocatalytic Asymmetric Synthesis Total Synthesis of Biologically Active N-Heterocycles Education 2003 – 2006 Ph.D Pharmaceutical Sciences in Medicinal Organic Chemistry, Chiba University, Japan 2001 – 2003 M.Sc. Pharmaceutical Sciences in Medicinal Organic Chemistry, Chiba University, Japan 1995 – 1999 B.Sc. Chemistry, (1st class honor), Chulalongkorn University, Thailand Work Experiences 2015 – present Research Scientist I, Chulabhorn Research Institute, Thailand 2006 – 2015 Research Scientist, Chulabhorn Research Institute, Thailand Awards 2015 Science and Technology Research Grant, Thailand Toray Science Foundation, Thailand 2014 ACP Lectureship to Taiwan, Asian CORE Program-NRCT 2000 – 2006 Monbukagakusho Scholarship, Japan 1998 Award for Excellence Academic Performance in Undergraduate Study, Dr. Tab Nilanidhi Foundation, Thailand 1997 Department of Chemistry Award of Excellence, Chulalongkorn University, Thailand 1995 – 1999 Development and Promotion of Science and Technology Talents Project (DPST), Thai government scholarship, Thailand Publications Selected Publications Disadee, W.; Trisupphakant, K.; Ruchirawat, S. Synthesis of Novel Fluorescent Bicyclic Amidines and Evaluation of Their Photophysical Properties. Heterocycles 2022, 105, 417–437. Disadee, W.; Ruchirawat, S. Oxazaborolidine-catalyzed Reductive Parallel Kinetic Resolution...

Name : Dr. Rattana Worayuthakarn (Research Scientist) Office Address : Room : R413 / R403B Laboratory of Medicinal Chemistry 54 Kamphaeng Phet 6 Talat Bang Khen, Lak Si, Bangkok 10210, Thailand Tel : +66 2553 8555 (ext. 3044) Email : [email protected] Research Interests Synthetic methodology Total synthesis of natural products Education 2001 – 2006 Ph.D Organic Chemistry, Mahidol University, Thailand 1998 – 2000 M.Sc. Organic Chemistry, Prince of Songkla University, Hat Yai, Thailand 1994 – 1997 B.Sc. Chemistry, Prince of Songkla University, Hat Yai, Thailand Work Experiences 2006 – 2019 Research Assistant, Chulabhorn Research Institute, Thailand 2019 – present Research Scientist, Chulabhorn Research Institute, Thailand Awards 2001-2003 Scholarship of The institutional strengthening program, Mahidol University 2001-2004 The Postgraduate Education and Research Program in Chemistry (PERCH), Mahidol University 2004-2006 Programme on Research and Development of Synthetic Drugs, Institute of Science and Technology for Research and Development, Mahidol University, Salaya Campus, Nakornpathom, Thailand Publications Selected Publications Worayuthakarn, R.; Suddee, N.; Nealmongkol, P.; Ruchirawat, S.; Thasana, N. Copper-mediated C-O/C-N Bond Formation: A Facile Synthesis of 3-Amidocoumarin, 3-Amidoazacoumarin, and N-Aeroylindole Derivatives. Synlett 2022, 33, 1431–1437. Worayuthakarn, R.; Deesiri, S.; Chainok, K.; Wannarit, N.; Ruchirawat, S.; Thasana, N. Highly Regioselective Tandem Reaction of Ene-Yne-Oxazolones Induced by H-Phosphonates: Construction of Phosphinylindane Derivatives. J. Org. Chem. 2021, 86, 9360–9383. Pramthaisong, C.; Worayuthakarn R.; Pharikronburee, V.; Duangthongyou, T.;...

Name : Dr. Poonsakdi Ploypradith (Expert Scientist) Office Address : Room : R517 / R403B Laboratory of Medicinal Chemistry 54 Kamphaeng Phet 6 Talat Bang Khen, Lak Si, Bangkok 10210, Thailand Tel : +66 2553 8555 (ext. 3069, 3044) Email : [email protected] Research Interests Synthetic methodology: stereoselective cyclization Total synthesis of natural products Medicinal chemistry of selected bioactive natural/synthetic compounds Education 1997 – 1999 Ph.D. Organic Chemistry, The Johns Hopkins University, U.S.A. 1994 – 1996 M.A. Organic Chemistry, The Johns Hopkins University, U.S.A. 1990 – 1994 B.A. Chemistry, The Johns Hopkins University, U.S.A. Work Experiences 2022 – present Expert Scientist, Chulabhorn Research Institute, Thailand 2015 – 2022 Research Scientist II, Chulabhorn Research Institute, Thailand 2009 – 2015 Research Scientist I, Chulabhorn Research Institute, Thailand 2000 – 2009 Research Scientist, Chulabhorn Research Institute, Thailand 2007 – present Lecturer, Program in Chemical Sciences, Chulabhorn Graduate Institute, Thailand Awards 2017 Lectureship Award to Taiwan (Asian Core Program) 2017 Lectureship Award to Korea (Asian Core Program) 2011 Lectureship Award to Hong Kong (Asian Core Program) 2011 Lectureship Award to Malaysia (Asian Core Program) 2009 Lectureship Award to Taiwan (Asian Core Program) 2009 Lectureship Award to Singapore (Asian Core Program) 2008 Lectureship Award to Korea (Asian Core Program) 2008 Lectureship Award to China (Asian Core Program) 1995 The Ernest M Marks Award for Excellence in...

Name : Dr. Paratchata Batsomboon (Research Scientist) Office Address : Room : R516C / R403A Laboratory of Medicinal Chemistry 54 Kamphaeng Phet 6 Talat Bang Khen, Lak Si, Bangkok 10210, Thailand Tel : +66 2553 8555 (ext. 3046, 3066) Email : [email protected] Research Interests Synthetic methodology Medicinal Chemistry in Molecular Modification of Small Molecules Computational Chemistry in Application of Spectroscopy and Reaction Mechanisms Education 2010 – 2016 Ph.D Organic Chemistry, Florida State University, U.S.A. 2007 – 2009 M.Sc. Chemical Biology, Chlabhorn Graduate Institute, Thailand 2003 – 2007 B.Sc. Chemistry, First Class Honors, Kasetsart University, Thailand Work Experiences 2020 – present Research Scientist, Chulabhorn Research Institute, Thailand 2017 – 2019 Postdoctoral Researcher, West Virginia University, U.S.A. 2009 – 2010 Research Assistant, Chulabhorn Research Institute, Thailand Awards 2007-2009 Chulabhorn Graduate Institute Scholarship 2003-2007 Science Achievement Scholarship of Thailand, SAST 2004-2006 Exceptional Academic Achievement Award, Faculty of Science, Kasetsart University Publications Selected Publications Fulo, H.F.; Rueb, N.J.; Gaston, R.; Batsomboon, P.; Ahmed, K.T.; Barrios, A.M.; Dudley, G.B. Synthesis of Illudalic acid and Analogous Phosphatase Inhibitors. Org. Biomol. Chem. 2021, 19, 10596–10600 Phumjan, T.; Songthammawat, P.; Jongcharoenkamol, J.; Batsomboon, P.; Ruchirawat, S.; Ploypradith, P. Substituted 9-Anthraldehydes from Dibenzocycloheptanol Epoxides via Acid-Catalyzed Epoxide Opening/Semipinacol Rearrangement. J. Org. Chem. 2021, 86, 13322–13349. Wright, A.K.; Batsomboon, P.; Dai, J.; Hung, I.; Zhou, H.-X.; Dudley, G.B.; Cross, T.A....

Name: Dr. Poramate Songthammawat (Research Scientist) Office Address: Room : 1 10 07-2 (CGI) Laboratory of Medicinal Chemistry 54 Kamphaeng Phet 6 Talat Bang Khen, Lak Si, Bangkok 10210, Thailand Tel: +66 2554 1900 (ext. 3001, 3018) Email: [email protected] Research Interests Synthetic methodology Total synthesis of natural products Education 2015 – 2020 Ph.D Chemical Biology, Chulabhorn Graduate Institute, Thailand. 2010 – 2012 M.Sc. Science (Organic Chemistry), Silpakorn University, Thailand 2006 – 2009 B.A. Science (Chemistry), Silpakorn University, Thailand Work Experiences 2020 – present Research Scientist, Chulabhorn Research Institute, Thailand 2019 “Visiting Scholar, Department of Chemistry, Colorado State University, USA (under supervision of late Prof. Robert M. Williams)” 2014 – 2015 PTT Global Chemical Public Company Limited (PTTGC), Thailand Awards 2017 The Royal Golden Jubilee Ph.D. Programme Scholarship 2015 The Scientist Development Scholarship in Honour of His Majesty the King Publications Selected Publications Tangdenpaisal, K.; Songthammawat, P.; Ruchirawat, S.; Ploypradith, P. Total Synthesis of Palodesangrens A and C. J. Org. Chem. 2022, 87, 386-398. Tangdenpaisal, K.*; Songthammawat, P.*; Akkarasereenon, K.; Chuayboonsong, K.; Ruchirawat, S.; Ploypradith, P. Total Synthesis of Palodesangren B Trimethyl Ether and D Dimethyl Ether via a Late-Stage Formation of 2H-Pyran-2-one of the Tetrahydrobenzo[c]pyranochromenone Core. J. Org. Chem. 2019, 84, 13410-13429. (with Supplementary Cover of the issue) *Contributed equally Songthammawat, P.; Wangngae, S.; Matsumoto, K.; Duangkamol, C.; Ruchirawat, S.;...

Name : Dr. Padon Chuentragool (Research Scientist)Office Address : Room : R411 / R403ALaboratory of Medicinal Chemistry54 Kamphaeng Phet 6 Talat Bang Khen, Lak Si, Bangkok 10210, ThailandTel : +66 2553 8555 (ext. -)Email : [email protected] Research InterestsSynthetic methodologyPhotocatalysisC-H functionalization Education2012 – 2018 Ph.D University of Illinois at Chicago, U.S.A.2009 – 2011 M.Sc. Chulalongkorn University, Thailand2003 – 2007 B.A. Chulalongkorn University, Thailand Work Experiences2021 – present Research Scientist, Chulabhorn Research Institute, Thailand2019-2021 Posdoctoral Researcher, University of Cambridge, UK Publications Selected Publications Proctor, R. S. J.; Chuentragool. P.; Colgan, A. C.; Phipps, R. J. Hydrogen Atom Transfer-Driven Enantioselective Minisci Reaction of Amides. J. Am. Chem. Soc. 2021, 143, 4928-4934. Chuentragool, P.*; Yadagiri, D.*; Morita, T.*; Sarkar, S.; Parasram, M.; Wang, Y.; Gevorgyan, V. Aliphatic Radical Relay Heck Reaction at Unactivated C(sp3)-H Sites of Alcohols. Angew. Chem. Int. Ed. 2019, 58, 1794-1798. *Contributed equally Chuentragool, P.; Parasram, M.; Shi, Y.; Gevorgyan, V. General, Mild, and Selective Method for Desaturation of Aliphatic Amines. J. Am. Chem. Soc. 2018, 140, 2465-2468. Parasram, M.*; Chuentragool, P.*; Sarkar, D.; Gevorgyan, V. Photoinduced Formation of Hybrid Aryl Pd-Radical Species Capable of 1,5-HAT: Selective Catalytic Oxidation of Silyl Ethers into Silyl Enol Ethers. J. Am. Chem. Soc. 2016, 138, 6340-6343. *Contributed equally Other Publications Pearce-Higgins, R.*; Hogenhout, L. N.*; Docherty, P. J.*; Whalley, D. M.; Chuentragool, P.; Lee,...