Dr. Punyawee Dulyayangkul

29 Jan 2023


Name: Dr. Punyawee Dulyayangkul

Office address: Research Laboratory of Biotechnology, Chulabhorn Research Institute,
54 Kamphaeng Phet 6 Talat Bang Khen, Lak Si, Bangkok 10210, Thailand
Tel: +66 25530 8555 (ext. 3264)
Positions: Researcher, Research Laboratory of Biotechnology, Chulabhorn Research Institute
E-mail[email protected]

Research Interests

  1. Antimicrobial resistance mechanisms
  2. Gram-negative bacterial pathogens
  3. Molecular biology

Education and Degrees

  • Chulabhorn Graduate Institute (CGI), Thailand, 2013-2018
    – Ph.D., Applied Biological Sciences (ABS): Environmental Health
  • Mahidol University International College (MUIC), Thailand, 2008-2011
    – B.Sc., Biological Science

Postdoctoral Experience

  • University of Bristol, UK, 2019-2022
    – Postdoctoral Research Associate, School of Cellular and Molecular Medicine


  • Royal Golden Jubilee (RGJ) Ph.D. Program Scholarship, 2015-2019
  • His Majesty The King Honour Celebration Scholarships Project for the Scientists Development, 2013-2018
  • First runner-up for the outstanding academic performance in the MUIC academic excellence scholarships, 2010
  • First runner-up for the outstanding academic performance in the MUIC academic excellence scholarships, 2009

ORCID iD: https://orcid.org/0000-0003-2289-145X


Satapoomin, N., Dulyayangkul, P., Avison, M.B. (2022). Klebsiella pneumoniae Mutants Resistant to Ceftazidime-Avibactam Plus Aztreonam, Imipenem-Relebactam, Meropenem-Vaborbactam, and Cefepime-Taniborbactam. Antimicrobial Agents and Chemotherapy, 66(4), e0217921. doi: 10.1128/aac.02179-21.

Alzayn, M., Dulyayangkul, P., Satapoomin, N., Heesom, K. J., & Avison, M. B. (2021). OmpF Downregulation Mediated by Sigma E or OmpR Activation Confers Cefalexin Resistance in Escherichia coli in the Absence of Acquired β-Lactamases. Antimicrobial Agents and Chemotherapy, 65(11), e01004-21. doi: 10.1128/AAC.01004-21.

Gibbon, M. J., Couto, N., David, S., Barden, R., Standerwick, R., Jagadeesan, K., Birkwood, H., Dulyayangkul, P., Avison, M.B., Kannan, A., Kibbey, D., Craft, T., Habib, S., Thorpe, H.A., Corander, J., Kasprzyk-Hordern, B. & Feil, E. J. (2021). A high prevalence of bla OXA-48 in Klebsiella (Raoultella) ornithinolytica and related species in hospital wastewater in South West England. Microbial genomics, 7(3). doi: 10.1099/mgen.0.000509.

Dulyayangkul, P., Satapoomin, N., Avison, M. B., Charoenlap, N., Vattanaviboon, P., & Mongkolsuk, S. (2021). Over-expression of hypochlorite inducible major facilitator superfamily (MFS) pumps reduces antimicrobial drug susceptibility by increasing the production of MexXY mediated by ArmZ in Pseudomonas aeruginosa. Frontiers in Microbiology, 11, 3376. doi: 10.3389/fmicb.2020.592153.

Booton, R. D., Meeyai, A., Alhusein, N., Buller, H., Feil, E., Lambert, H., Mongkolsuk, S., Pitchforth, E., Reyher, K. K., Sakcamduang, W., Satayavivad, J., Singer, A. C., Sringernyuang, L., Thamlikitkul, V., Vass, L., OH-DART Study Group, Avison, M. B. & Turner, K. M. E. (2021). One Health drivers of antibacterial resistance: quantifying the relative impacts of human, animal and environmental use and transmission. One Health, 12, 100220. doi: 10.1016/j.onehlt.2021.100220.

Cheung, C. H. P., Dulyayangkul, P., Heesom, K. J., & Avison, M. B. (2020). Proteomic Investigation of the Signal Transduction Pathways Controlling Colistin Resistance in Klebsiella pneumoniae. Antimicrobial Agents and Chemotherapy. doi: 10.1128/AAC.00790-20.

Dulyayangkul, P., Douglas, E., Lastovka, F., & Avison, M. B. (2020). Resistance to Ceftazidime/Avibactam plus Meropenem/Vaborbactam When Both Are Used Together Is Achieved in Four Steps in Metallo-β-Lactamase-Negative Klebsiella pneumoniae. Antimicrobial Agents and Chemotherapy. doi: 10.1128/AAC.00409-20.

 Dulyayangkul, P., Ismah, W. A. K. W. N., Douglas, E. J., & Avison, M. B. (2020). Mutation of kvrA causes OmpK35/36 porin downregulation and reduced meropenem/vaborbactam susceptibility in KPC-producing Klebsiella pneumoniae. Antimicrobial Agents and Chemotherapy. doi: 10.1128/AAC.02208-19.

Dulyayangkul, P., Calvopiña, K., Heesom, K. J., & Avison, M. B. (2020). Novel mechanisms of efflux-mediated levofloxacin resistance and reduced amikacin susceptibility in Stenotrophomonas maltophilia. Antimicrobial Agents and Chemotherapy, 65(1), e01284-20. doi: 10.1128/AAC.01284-20.

Calvopiña, K., Dulyayangkul, P., Heesom, K. J., & Avison, M. B. (2019). TonB‐dependent uptake of β‐lactam antibiotics in the opportunistic human pathogen Stenotrophomonas maltophilia. Molecular microbiology. doi: 10.1111/mmi.14434.

Calvopiña, K., Dulyayangkul, P., & Avison, M. B. (2019). Mutations in Ribosomal Protein RplA or Treatment with Ribosomal Acting Antibiotics Activate Production of Aminoglycoside Efflux Pump SmeYZ in Stenotrophomonas maltophilia. Antimicrobial agents and chemotherapy. doi: 10.1128/AAC.01524-19.

Whittle, E. E., Legood, S. W., Alav, I., Dulyayangkul, P., Overton, T. W., & Blair, J. (2019). Flow Cytometric Analysis of Efflux by Dye Accumulation. Frontiers in microbiology, 10, 2319. doi: 10.3389/fmicb.2019.02319.

Vattanaviboon, P., Dulyayangkul, P., Mongkolsuk, S., & Charoenlap, N. (2018). Overexpression of Stenotrophomonas maltophilia major facilitator superfamily protein MfsA increases resistance to fluoroquinolone antibiotics. Journal of Antimicrobial Chemotherapy, 73(5), 1263-1266. doi: 10.1093/jac/dky024.

Dulyayangkul, P., Charoenlap, N., Srijaruskul, K., Mongkolsuk, S., & Vattanaviboon, P. (2016). Major facilitator superfamily MfsA contributes to multidrug resistance in emerging nosocomial pathogen Stenotrophomonas maltophiliaJournal of Antimicrobial Chemotherapy71(10), 2990-2991. doi: 10.1093/jac/dkw233.

Chancharoensin, S. Dulyayangkul, P., & Aung, L. (2013). Alkaline Mannanase Production from Bacillus subtilis Strain C3 in Complex Medium Containing Coconut Pulp. International Journal of Biotechnology & Biochemistry, 9(2), 211-219.

Chancharoensin, S., Srimahaeak, T., Dulyayangkul, P., & Luechai, S. (2012). Production of Reducing Sugar from Acid Pretreated Leaf Litter Using Crude Enzyme from Aspergillus niger Strain AK10. International Journal of Biotechnology & Biochemistry, 8(3), 279-287.


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