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Medicinal Chemistry

Medicinal Chemistry

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Synthesis, biological evaluation, molecular docking, and in silico ADME predictions of huperzine: A derivative for the novel protective application against neurodegenerations

Homkajorn B, Nilsu T, Suntararuks S, Saparpakorn P, Ingkaninan K, Limpeanchob N, Satayavivad J, Ruchirawat S, Thasana N*

Chem Asian J. 2025;2025:e202401950.

Synthesis, anti-proliferation, apoptosis induction in breast cancer cells, and aromatase inhibition of coumarin-triazole hybrids: In vitro and in silico studies

Saekee A, Sooknual P, Punpai S, Prachayasittikul V*, Hongthong S, Tanechpongtamb W, Prachayasittikul S, Ruchirawat S, Prachayasittikul V, Pingaew R*

Arch Biochem Biophys. 2025;765:110308.

Hypervalent iodine(III)-mediated oxidative cyclization of exo-cyclic ene-carbamate to tetrahydroisoquinoline-oxazol-2(3H)-one derivatives

Limjirawatthana S, Ploypradith P, Ruchirawat S, Theppitak C, Ieawsuwan W

Chem Asian J. 2025. (Inpress Article)

Molecular engineering of cordycepin derivatives for enhanced biological activity and stability

Gu Y, Yu W, Li X, Fan Y, Liu Y, Tummatorn J, Jiang S, Yang J

ChemMedChem. 2025. (Inpress Article)

Chromones from stems of Harrisonia perforata

Khumsubdee S, Prachyawarakorn V, Mahidol C, Ploypradith P, Ruchirawat S, Pailee P

Nat Prod Res. 2025. (Inpress Article)

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