Dr. Thitirat Ngaotepprutaram
54 Kamphaeng Phet 6 Talat Bang Khen, Lak Si, Bangkok 10210, Thailand
- 1999 – 2003 B.S. (1st Hons) in Genetics, Kasetsart University, Thailand
- 2003 – 2005 M.Sc. in Molecular Genetics and Genetic Engineering, Mahidol University, Thailand
- 2006 – 2013 Ph.D. with Dual-Major Program in Pharmacology & Toxicology and Environmental Toxicology, Michigan State University, USA
- Immunotoxicity of environmental toxicants
- Technical expertise includes flow/phosphoflow cytometry, qRT-PCR, gel-shift assay, luciferase reporter assay, ELISA, ELISPOT and mouse and human immune cell isolation and culture.
– Ngaotepprutaram T, Kaplan BLF, and Kaminski NE. Suppression by ∆(9)-tetrahydrocannabinol of the primary Immunoglobulin M response by human peripheral blood B cells is associated with impaired STAT3 activation. Toxicology 9;310:84-91, 2013.
– Ngaotepprutaram T, Kaplan BLF, and Kaminski NE. Impaired NFAT and NFB activation are involved in auppression of CD40 ligand expression by ∆(9)-tetrahydrocannabinol in human CD4+ T cells. Toxicol Appl Pharmacol. 15;273(1):209-18.
– Ngaotepprutaram T, Kaplan BLF, Crawford RB, and Kaminski NE. Differential modulation by delta9-tetrahydrocannabinol (∆9-THC) of CD40 ligand (CD40L) expression in activated mouse splenic CD4+ T cells. J Neuroimmune Pharmacol. 7(4):969-80, 2012
– Kaplan BLF, Lawver JE, Karmaus PW, Ngaotepprutaram T, Birmingham NP, Harkema JR and Kaminski NE. The effects of targeted deletion of cannabinoid receptors CB1 and CB2 on intranasal sensitization and challenge with adjuvant-free ovalbumin. Toxicol Pathol 38(3):382-92, 2010.
– Lu H, Kaplan BL, Ngaotepprutaram T, Kaminski NE: Suppression of T cell costimulator ICOS by Delta(9)-Tetrahydrocannabinol. J. Leukoc. Biol. 85(2): 322-9, 2009.