Dr. Pattama Singhirunnusorn

01 Apr 2014
0

Name: Dr. Pattama Singhirunnusorn

Office address: Research Laboratory of Chemical Carcinogenesis, Chulabhorn Research Institute,
54 Kamphaeng Phet 6 Talat Bang Khen, Lak Si, Bangkok 10210, Thailand
Tel: +6625538555 ext. 3135 (office), +66875915431 (mobile)
Fax: +6625538572

Positions: Research Scientist, Research Laboratory of Chemical Carcinogenesis, Chulabhorn Research Institute
Email: pattama@cri.or.th

Website: 

Research Interests

  • Signal transduction
  • Cell and Molecular Biology

Education and Degrees: 

  • B.Sc. (Chemistry), Suan Dusit Rajabhat University, Bangkok, Thailand, 19941997
  • M.Sc. (Pharmaceutical Chemistry), Mahidol University, Bangkok, Thailand, 19992002
  • Ph.D. (Pharmaceutical Science), University of Toyama, Toyama, Japan, 20022005

Academic Positions

  • Researcher, Department of Pharmacognosy, Faculty of pharmacy, Mahidol University, Thailand, 1998
  • Postdoctoral Fellow, Division of Pathogenic Biochemistry, Department of Bioscience, Institute of Natural Medicine, University of Toyama, Japan, 20062008
  • Researcher, Chemical Carcinogenesis laboratory, Chulabhorn Research Institute, 2008present

Academic Activities

Local Activities

  • Project proposal committee (20152016), Thesis defend committee (20162017), AntiAging and Regenerative Medicine Faculty, Dhurakij Pundit University   

Fellowships

  • Postdoctoral Fellow, Division of Pathogenic Biochemistry, Department of Bioscience, Institute of Natural Medicine, University of Toyama, Japan, 20062008

International Awards & Honours

  • Toyama New Industry Organization Grants, Japan, 20062007
  • Monbukagakusho Scholarship, Japan, 20022005

Local Awards & Honours

  • Poster award at The 10th National Cancer Conference, Bangkok, Thailand, 2009

ORCID iDhttps://orcid.org/0000000280855417

Publications

A. Research Articles in International Journals

  • Singhirunnusorn, P., Moolmuang, B., Lirdprapamongkol, K., & Ruchirawat, M. (2018). Arsenite exposure potentiates apoptosisinducing effects of tumor necrosis factoralphathrough reactive oxygen species. J Toxicol Sci, 43(2), 159169. doi:10.2131/jts.43.159 
  • Moolmuang, B., Singhirunnusorn, P., & Ruchirawat, M. (2016). Effects of 5Aza2′Deoxycytidine, Bromodeoxyuridine, Interferons and Hydrogen Peroxide on Cellular Senescence in Cholangiocarcinoma Cells. Asian Pac J Cancer Prev, 17(3), 957963. doi:10.7314/apjcp.2016.17.3.957
  • Shin, M. S., Shinghirunnusorn, P., Sugishima, Y., Nishimura, M., Suzuki, S., Koizumi, K., . . . Sakurai, H. (2009). Cross interference with TNFalphainduced TAK1 activation via EGFRmediated p38 phosphorylation of TAK1binding protein 1. Biochim Biophys Acta, 1793(7), 11561164. doi:10.1016/j.bbamcr.2009.04.005 
  • Nishimura, M., Shin, M. S., Singhirunnusorn, P., Suzuki, S., Kawanishi, M., Koizumi, K., . . . Sakurai, H. (2009). TAK1mediated serine/threonine phosphorylation of epidermal growth factor receptor via p38/extracellular signalregulated kinase: NF{kappa}Bindependent survival pathways in tumor necrosis factor alpha signaling. Mol Cell Biol, 29(20), 55295539. doi:10.1128/MCB.0037509
  • Singhirunnusorn, P., Ueno, Y., Matsuo, M., Suzuki, S., Saiki, I., & Sakurai, H. (2007). Transient suppression of ligandmediated activation of epidermal growth factor receptor by tumor necrosis factoralpha through the TAK1p38 signaling pathway. J Biol Chem, 282(17), 1269812706. doi:10.1074/jbc.M608723200
  • Suzuki, S., Singhirunnusorn, P., Mori, A., Yamaoka, S., Kitajima, I., Saiki, I., & Sakurai, H. (2007). Constitutive activation of TAK1 by HTLV1 taxdependent overexpression of TAB2 induces activation of JNKATF2 but not IKKNFkappaB. J Biol Chem, 282(35), 2517725181. doi:10.1074/jbc.C700065200
  • Suzuki, S., Singhirunnusorn, P., Nakano, H., Doi, T., Saiki, I., & Sakurai, H. (2006). Identification of TNFalpharesponsive NFkappaB p65binding element in the distal promoter of the mouse serine protease inhibitor SerpinE2. FEBS Lett, 580(13), 32573262. doi:10.1016/j.febslet.2006.04.086
  • Choo, M. K., Kawasaki, N., Singhirunnusorn, P., Koizumi, K., Sato, S., Akira, S., . . . Sakurai, H. (2006). Blockade of transforming growth factorbetaactivated kinase 1 activity enhances TRAILinduced apoptosis through activation of a caspase cascade. Mol Cancer Ther, 5(12), 29702976. doi:10.1158/15357163.MCT060379
  • Singhirunnusorn, P., Suzuki, S., Kawasaki, N., Saiki, I., & Sakurai, H. (2005). Critical roles of threonine 187 phosphorylation in cellular stressinduced rapid and transient activation of transforming growth factorbetaactivated kinase 1 (TAK1) in a signaling complex containing TAK1binding protein TAB1 and TAB2. J Biol Chem, 280(8), 73597368. doi:10.1074/jbc.M407537200
  • Sakurai, H., Singhirunnusorn, P., Shimotabira, E., Chino, A., Suzuki, S., Koizumi, K., & Saiki, I. (2005). TAK1mediated transcriptional activation of CD28responsive element and AP1binding site within the IL2 promoter in Jurkat T cells. FEBS Lett, 579(29), 66416646. doi:10.1016/j.febslet.2005.10.059 
  • Lirdprapamongkol, K., Sakurai, H., Kawasaki, N., Choo, M. K., Saitoh, Y., Aozuka, Y., . . . Saiki, I. (2005). Vanillin suppresses in vitro invasion and in vivo metastasis of mouse breast cancer cells. Eur J Pharm Sci, 25(1), 5765. doi:10.1016/j.ejps.2005.01.015

 

Tags

Share this