Toxicoproteomic study of fipronil in SH-SY5Y cells reveals induction of endoplasmic reticulum stress and necrotic cell death as neurodegenerative mechanisms

14 Oct 2025
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Toxicoproteomic study of fipronil in SH-SY5Y cells reveals induction of endoplasmic reticulum stress and necrotic cell death as neurodegenerative mechanisms

Ruangjaroon T, Paricharttanakul NM, Chokchaichamnankit D, Srisomsap C, Lirdprapamongkol K, Svasti J

Toxicol Vitro. 2025;108:106098.

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Juberg-Hayward syndrome and Roberts syndrome are allelic, caused by mutations in ESCO2. Kantaputra PN*, Dejkhamron P, Tongsima S, Ngamphiw C, Intachai W, Ngiwsara L, Sawangareetrakul P, Svasti J, Olsen B, Cairns JRK, Bumroongkit K. Arch Oral Biol. 2020 Nov;119:104918.

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