Protein Modification via Nitrile Oxide-Dehydroalanine Cycloaddition: Formation of Isoxazoline Ring on the Protein Backbone

20 Sep 2023
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Protein Modification via Nitrile Oxide-Dehydroalanine Cycloaddition: Formation of Isoxazoline Ring on the Protein Backbone

Phanumartwiwath A, Kesornpun C, Chokchaichamnankit D, Khongmanee A, Diskul-Na-Ayudthaya P, Ruangjaroon T, Srisomsap C, Kittakoop P, Svasti J, Ruchirawat S

Chembiochem. 2023.
(In press)

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An engineered cell line lacking OGG1 and MUTYH glycosylases implicates the accumulation of genomic 8-oxoguanine as the basis for paraquat mutagenicity. Tajai, P., Fedeles, B. I., Suriyo, T., Navasumrit, P., Kanitwithayanun, J., Essigmann, J. M., &Satayavivad, J. (2018). Free Radical Biology and Medicine, 116, 64-72.
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