Dr. Aurapat Ngamnithiporn

26 Jan 2023

Name : Dr. Aurapat Ngamnithiporn (Research Scientist)
Office Address : Room : R413 / R403A
Laboratory of Medicinal Chemistry
54 Kamphaeng Phet 6 Talat Bang Khen, Lak Si, Bangkok 10210, Thailand
Tel : +66 2553 8555 (ext. 3042)
Email : [email protected]

Research Interests
Synthetic methodology
Asymmetric catalysis
Total synthesis of natural products

2018 – 2021 Ph.D Organic Chemistry, California Institute of Technology, U.S.A.
2015 – 2018 M.Sc. Organic Chemistry, California Institute of Technology, U.S.A.
2011 – 2015 B.A. Chemistry, Magna cum laude, Carleton College, U.S.A.

Work Experiences
2021 – present Research Scientist, Chulabhorn Research Institute, Thailand

2010 – 2021 Royal Thai Government Scholarship
2015 ACS Undergraduate Award in Organic Chemistry, U.S.A.
2015 Sigma Xi Undergraduate Research Award, Carleton College, U.S.A.
2015 Richard Ramette Teaching Award, Carleton College, U.S.A.
2015 Phi Beta Kappa National Honor Society, Carleton College, U.S.A.
2015 Jerry Mohrig Prize in Chemistry, Carleton College, U.S.A.

Selected Publications

  1. Ngamnithiporn, A.; Chuentragool, P.; Ploypradith, P.; Ruchirawat, S. Syntheses of 3-Aryl Tetrahydroisoquinolines via an Intermolecular [4 + 2] Cycloaddition of Sultines with Imines. Org. Lett. 2022, 24, 4192–4196.
  2. Kim, A. N.; Ngamnithiporn, A.; Bartberger, M. D.; Stoltz, B. M. Iridium-Catalyzed Asymmetric Trans-Selective Hydrogenation of 1,3-Disubstituted Isoquinolines. Chem. Sci. 2022, 13, 3227–3232.
  3. Kim, A. N.;* Ngamnithiporn, A.;* Welin, E. R.; Daiger, M. T., Grunanger, C. U.; Bartberger, M. D.; Virgil, S. C.; Stoltz, B. M. Iridium-Catalyzed Enantioselective and Diastereoselective Hydrogenation of 1,3-Disubstituted Isoquinolines. ACS Catalysis 2020, 10, 3241–3248. *Contributed equally
  4. Welin, E. R.; Ngamnithiporn, A.; Klatte, M.; Lapointe, G.; Pototschnig, G. M.; McDermott, M. S. J.; Conklin, D.; Gilmore, C. D.; Tadross, P. M.; Haley, C. K.; Negoro, K.; Glibstrup, E.; Grunanger, C. U.; Allan, K. M.; Virgil, S. C.; Slamon, D. J.; Stoltz, B. M. Concise Total Syntheses of (–)-Jorunnamycin A and (–)-Jorumycin Enabled by Asymmetric Catalysis. Science 2019, 363, 270–275.

Other Publications

  1. Reimann, C.;* Ngamnithiporn, A.;* Hayashida, K.; Saito, D.; Korch, K.; Stoltz, B. M. The Enantioselective Synthesis of Eburnamonine, Eucophylline, and 16’-epi-Leucophyllidine. Angew. Chem. Int. Ed. 2021, 60, 17957–17962. *Contributed equally
  2. Enantioselective Synthesis of Highly Oxygenated Acyclic Quaternary Center-Containing Building Blocks via Palladium-Catalyzed Decarboxylative Allylic Alkylation of Cyclic Siloxyketones. Chem. Sci. 2020, 11, 11068–11071.
  3. Yamano, M. M.; Knapp, R. R.; Ngamnithiporn, A.; Ramirez, M.; Houk, K. N.; Stoltz, B. M.; Garg, N. K. Cycloadditions of Oxacyclic Allenes and a Catalytic Asymmetric Entryway to Enantioenriched Cyclic Allenes. Angew. Chem. Int. Ed. 2019, 58, 5653–5657.
  4. Ngamnithiporn, A.; Jette, C. I.; Bachman, S.; Virgil, S. C.; Stoltz, B. M. Nickel-Catalyzed Enantioselective Allylic Alkylation of Lactones and Lactams with Unactivated Allyilc Alcohols. Chem. Sci. 2018, 9, 2547–2551.
  5. Hayashibara, H.; Ngamnithiporn, A.; Nomura, K. Reactions of (Arylimido)vanadium(V)-Trialkyl Complexes with Phenols: Effects of Arylimido Ligands and Phenols for Formation of the Vanadium Phenoxides. ACS Omega 2019, 4, 5818–5828.
  6. White, M. T.; Hofmeister, G. E.; Hodges, C. J.; Jensen, L. T.; Keys, S. H.; Ngamnithiporn, A.; Janzen, D. E. Crystal Structures of trans-acetyldicarbonyl(η5-cyclopentadienyl)(dimethyl-phenyl phosphane)molybdenum(II) and trans- acetyldicarbonyl(η5-cyclopentadienyl)(ethyl-diphenyl phosphane)molybdenum(II). Acta Crystallogr., Sect. E: Struct. Rep. Online 2014, 70, 216–220.



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